Noradrenalin-Wiederaufnahme-Hemmer (SNRI)

/652 Kommentare/in , /von

Durch die Wiederaufnahme eines ausgeschütteten Botenstoffes wird dessen Wirkung beendet. Noradrenalin-Wiederaufnahme-Hemmer, kurz SNRI genannt, sind Antidepressiva, die relativ spezifisch die Wiederaufnahme des Botenstoffes Noradrenalin in die präsynaptischen Nervenzell-Endigungen hemmen und die Verweildauer dieses Botenstoffes im sogenannten präsynaptischen Spalt erhöhen.

Die auf diesem Wege erreichte verstärkte und verlängerte Wirkung des Noradrenalins wirkt gegen Depression, insbesondere gegen solche Formen, bei denen im Hirn ein relativer Noradrenalinmangel vorliegt.

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